Original paper

Urodynamic evaluation before and after continuous intrathecal Baclofen infusion (ITB) in patients unresponsive wakefulness syndrome and minimally conscious state

  • DONATELLA GIRAUDO
  • FRANCESCA GOZZERINO
  • GIANFRANCO LAMBERTI
  • ELENA ANTONIONO
  • CLAUDIO CALIFANO
  • MARIA TERESA FILOCAMO
  • GIUSEPPE MASSAZZA

Pelviperineology 2017;36(2):60-62

Only a few reports have been published on acquired brain injury (ABI), especially on the correlation of urodynamic findings. The aim of this study is to urodinamically assess bladder function in patients on Unresponsive Wakefullness Syndrome (UWS) and Minimally Conscious State (MCS) before and after Intrathecal Baclofen Therapy (IBT) for supraspinal spasticity. After IBT there was a significant increase of Maximum Cystometric Capacity (MCC) and a reduction of Detrusor Leak Point Pressure (DLPP). Accordingly, an increase in Post Void Residual PVR in the first month was identified. While these results may seem a positive consequence of the therapy, they must be related to the type of patient treated, indeed the absence of a detrusor contraction supported by supraspinal centres can create an increase of the post-void residual. However, this discrepancy was filled out six months after implantation and the PVR returns comparable to the baseline.

Keywords: Intrathecal Baclofen therapy; Minimally conscious state; Unresponsive wakefullness syndrome; Urodynamics.