pelviperineology. 2016; 35(4): 113-115 | DOI:

Effectiveness of sacral neuromodulation in the management of refractory bladder pain syndrome

MARIA ANGELA cerruto¹, CAROLINA D’ELIA¹, ALESSANDRA GOZZO¹, FRANCESCA CAVICCHIOLI¹, ANILA MINJA¹, GIOVANNI CACCIAMANI¹, DAVIDE DE MARCHI¹, ANTONIO D’AMICO¹, ALESSANDRA SARTI¹, MATTEO BALZARRO¹, ANTONIO BENITO PORCARO¹, SALVATORE SIRACUSANO¹, WALTER ARTIBANI¹, FRANCESCO CAPPELLANO^2
1AOUI of Verona, Urology, ²IRCCS Multimedica Milan, Urology

Introduction and aim of the study. Bladder Pain syndrome (BPs) is a complex pathology, with a prevalence ranging from 0.06% to 30%. in patients refractory to first line treatment, sacral neuromodulation (snm) can reduce BPs symptoms and improve patients’ lower urinary tract symptoms (Luts) associated. the aim of this study was to evaluate the effectiveness of snm for the treatment of symptoms in patients with refractory BPs. Materials and methods: the data regarding patients undergoing snm refractory to medical/conservative therapy, who underwent interstim® snm 2012 and 2014 in a single italian centre, were retrospectively evaluated. Bladder pain was assessed with a 0-10 Visual analogue scale (Vas) before and one year after the treatment and at the last follow-up visit, whereas Luts were evaluated using a three-day bladder diary. Results: twenty-three patients underwent first stage unilateral s3 stimulation; median age was 56 years and mean follow-up was 32 months; 78% of the patients showed a significant improvement and underwent a definitive implant. Patients’ reported pain score decreased from a mean of 8 at baseline to 3 at one-year follow-up (p < 0.001). urgency decreased from 4.6 ± 2.4 up to 1.3 ± 1.9 (p < 0.001). daily urinary frequency improved from 12.7 ± 4.8 times up to 8.7 ± 2.8 (p < 0.001) and nocturia decreased from 2.5 ± 1.9 up to 0.7 ± 1 (p < 0.001). mean voided volume increased from 145.4 ± 70.5 ml to 208.2 ± 73.4 ml (p < 0.001). clinical effectiveness was maintained in the last follow-up visit. conclusions: snm appears to be effective and safe in treating refractory BPs with associated Luts.

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Cite This Article

cerruto M, D’ELIA C, GOZZO A, CAVICCHIOLI F, MINJA A, CACCIAMANI G, DE MARCHI D, D’AMICO A, SARTI A, BALZARRO M, PORCARO A, SIRACUSANO S, ARTIBANI W, CAPPELLANO F. Effectiveness of sacral neuromodulation in the management of refractory bladder pain syndrome. 2016; 35(4): 113-115

Corresponding Author: cerruto M.

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