pelviperineology. 2017; 36(2): 60-62 | DOI:

Urodynamic evaluation before and after continuous intrathecal Baclofen infusion (ITB) in patients unresponsive wakefulness syndrome and minimally conscious state

DONATELLA GIRAUDO¹, FRANCESCA GOZZERINO², GIANFRANCO LAMBERTI³, ELENA ANTONIONO³, CLAUDIO CALIFANO³, MARIA TERESA FILOCAMO⁴, GIUSEPPE MASSAZZA^2
1Dipartimento di Urologia - Ospedale S. Raffaele Turro - Milano, ²Scuola di Specializzazione in Medicina Fisica e Riabilitativa - Università di Torino, ³S.C. Neuroriabilitazione ASL CN1 - Cuneo, ⁴S.C. Urologia Ospedale Savigliano ASL CN1 - Cuneo

Only a few reports have been published on acquired brain injury (ABI), especially on the correlation of urodynamic findings. The aim of this study is to urodinamically assess bladder function in patients on Unresponsive Wakefullness Syndrome (UWS) and Minimally Conscious State (MCS) before and after Intrathecal Baclofen Therapy (IBT) for supraspinal spasticity. After IBT there was a significant increase of Maximum Cystometric Capacity (MCC) and a reduction of Detrusor Leak Point Pressure (DLPP). Accordingly, an increase in Post Void Residual PVR in the first month was identified. While these results may seem a positive consequence of the therapy, they must be related to the type of patient treated, indeed the absence of a detrusor contraction supported by supraspinal centres can create an increase of the post-void residual. However, this discrepancy was filled out six months after implantation and the PVR returns comparable to the baseline.

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Cite This Article

GIRAUDO D, GOZZERINO F, LAMBERTI G, ANTONIONO E, CALIFANO C, FILOCAMO M, MASSAZZA G. Urodynamic evaluation before and after continuous intrathecal Baclofen infusion (ITB) in patients unresponsive wakefulness syndrome and minimally conscious state. 2017; 36(2): 60-62

Corresponding Author: GIRAUDO D.

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