ABSTRACT

Aim:

To test the concepts and predictions of Integral Theory System (ITS), that pelvic prolapse and symptoms are caused by laxity in vagina / suspensory ligaments.

Methods:

A Popper’s deductive method was applied. The data from published papers in the November 2012 IUJ was tested against concepts and predictions of the ITS. If these concepts and predictions could not explain that data, the ITS was considered invalid. Only descriptive papers were excluded.

Results:

Of 13 papers analysed, 12 were deemed logically consistent with ITS. Overactive Bladder (OAB) and low urethral pressure papers were attributed to loose ligament weakening of musculoelastic mechanisms, diabetic urge symptoms to greater ligament damage by macrosomia; pregnancy effects on hiatal measurements and symptoms by relaxin on collagen crossbonding; symptom improvement with vit D with positive effect on collagen metabolism and ligament strength. The ITS could not explain longer-term improvement of urge symptoms by posterior tibial nerve stimulation.

Conclusion:

There was strong logical consistency between ITS and 12/13 IUJ November 2012 papers.