ABSTRACT

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a frequent disease affecting men of all ages. Chronic prostatitis can significantly impair quality of life. Symptoms attributed to CP/CPPS are heterogenous. Patients with CP/CPPS present an individual etiological and symptomatology profile resulting in an unique clinical phenotype. Research efforts were made to define multimodal therapeutic strategies addressing the wide array of signs and symptoms. A clinical phenotyping system has been suggested clinically directive to focus on the symptoms of the patients. This system contains six major complain domains of CP/CPPS patients: urinary, psychosocial, organ specific, infection, neurologic and tenderness of skeletal muscles (UPOINT). Recently, the system was modified by adding the sexual dysfunction as a domain to create UPOINTS. Promising results have currently been reported from multimodal approaches of CP/CPPS therapy as it aims to offer a personalized combination therapy.