pelviperineology. 2008; 27(4): 143-144 | DOI:

Neurophysiological modification of pelvic floor parameters during sacral nerve neuromodulation

ELENA ANDRETTA¹, EDOARDO OSTARDO², CRISTINA ZULIANI³, LAURA DE BIAGGI⁴, TIZIANA DE SANTO^4
1Department of Urology - General Hospital Dolo (Venice), ²Department of Urology - City Hospital S.ta Maria degli Angeli Pordenone, ³Department of Neurology - General Hospital Mirano (Venice), ⁴Medtronic Italia

Significant changes in function of perineal innervation have been observed in 27 patients treated with sacral nerve neuromodulation. Using electrodiagnostic techniques, performed with an Interstim implantable pulse generator switched on and off, we observed that sacral nerve neuromodulation increases the amplitude of voluntary contraction of the urethral sphincter, decreases the duration of motor unit potentials at rest in both sphincters and reduces latencies of pudendal nerve terminal motor bilaterally. These results suggest a greater recruitment of pelvic muscular fibers and a better synchronization of the fibers firing. Sacral nerve neuromodulation probably increases the motor conduction velocity of pudendal nerves and so suppresses integration between peripheral innervation and spinal cord.

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Cite This Article

ANDRETTA E, OSTARDO E, ZULIANI C, DE BIAGGI L, DE SANTO T. Neurophysiological modification of pelvic floor parameters during sacral nerve neuromodulation. 2008; 27(4): 143-144

Corresponding Author: ANDRETTA E.

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